
Microbiology Project Topics
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Students can choose from a wide list of ready-made Microbiology project topics or request a fully customized report prepared according to their specific research area. Every project is developed purely for learning and reference purposes, helping you understand report structure, research methodology, and analysis so that you can confidently prepare your own Microbiology academic work.

Microbiology 500 Topics For Project Report
Microbiology Project Topics List (1–100)
1. Isolation and characterization of antibiotic-producing microorganisms
2. Study of antimicrobial activity of medicinal plant extracts
3. Bacterial contamination of street foods
4. Microbial quality analysis of drinking water
5. Isolation of coliform bacteria from sewage samples
6. Study of fungal flora from spoiled fruits
7. Effect of temperature on bacterial growth rate
8. Microbial analysis of milk and dairy products
9. Antibiotic resistance profiling of hospital isolates
10. Isolation of Escherichia coli from contaminated water sources
11. Screening of soil microbes for enzyme production
12. Role of probiotics in gut microbiota balance
13. Study of biofilm formation in pathogenic bacteria
14. Bacteriological examination of air in hospital environments
15. Identification of fungi from damp building materials
16. Antimicrobial resistance in urinary tract infection pathogens
17. Isolation and identification of lactic acid bacteria from curd
18. Microbial degradation of plastic waste
19. Screening of actinomycetes for antibiotic potential
20. Bioremediation of oil-contaminated soil
21. Isolation of nitrogen-fixing bacteria from root nodules
22. Microbial spoilage of bakery products
23. Effect of UV radiation on bacterial DNA
24. Study of pathogenic bacteria from wound infections
25. Screening of yeast for bioethanol production
26. Isolation of halophilic bacteria from saline environments
27. Microbial succession during composting
28. Bacteriological analysis of bottled drinking water
29. Effect of pH on enzyme activity of microorganisms
30. Screening of fungi for amylase production
31. Identification of airborne microorganisms in laboratories
32. Study of bacterial diversity in polluted water
33. Isolation of phosphate-solubilizing bacteria from soil
34. Characterization of heavy metal-resistant microbes
35. Detection of Salmonella in poultry products
36. Antibacterial activity of natural honey
37. Study of biofertilizer-producing microorganisms
38. Isolation of thermophilic bacteria from hot springs
39. Antifungal activity of essential oils
40. Isolation and characterization of marine microorganisms
41. Microbiological quality of raw vegetables
42. Study of mold growth on different food surfaces
43. Detection of microbial contamination in cosmetics
44. Role of microbes in biodegradation of pesticides
45. Screening of microorganisms for lipase enzyme
46. Comparative study of disinfectants on bacterial cultures
47. Isolation of antibiotic-resistant Staphylococcus aureus
48. Bacteriological analysis of public swimming pools
49. Study of yeast fermentation in fruit juices
50. Effect of salt concentration on microbial growth
51. Role of microbes in biogas production
52. Detection of coliforms in packaged juices
53. Isolation of endophytic fungi from medicinal plants
54. Microbial analysis of soil from agricultural fields
55. Study of antibiotic synergy using disk diffusion method
56. Antimicrobial screening of herbal extracts
57. Bacteriological quality of street-vended juices
58. Isolation of pigment-producing bacteria
59. Characterization of cellulase-producing microbes
60. Study of microbial contamination in meat markets
61. Microbial quality analysis of hospital surfaces
62. Isolation of psychrophilic bacteria from refrigerated foods
63. Detection of mycotoxins in stored grains
64. Study of probiotics in fermented milk
65. Isolation of sulfate-reducing bacteria from sediments
66. Bacteriological analysis of sewage effluent
67. Screening of microorganisms for protease production
68. Study of bacterial flora of human skin
69. Effect of antibiotics on microbial population in soil
70. Isolation of microorganisms from fermented foods
71. Study of antibiotic resistance genes using PCR
72. Characterization of biofilm-forming bacteria
73. Isolation of cellulolytic fungi from decaying wood
74. Study of microbial contamination in hospital air
75. Biodegradation of dyes using bacterial isolates
76. Microbiological study of fermented pickles
77. Detection of Listeria monocytogenes in dairy products
78. Isolation of bacteria from petroleum-contaminated soil
79. Comparative study of bacterial growth in different media
80. Study of microbial quality of bottled milk
81. Isolation of antibiotic-producing Streptomyces
82. Study of microbial flora in oral cavity
83. Bacterial analysis of hand swabs of food handlers
84. Microbial degradation of cellulose from agricultural waste
85. Effect of temperature on fungal spore germination
86. Isolation of methanogenic bacteria from sludge
87. Study of food spoilage bacteria from canned products
88. Detection of Vibrio species in seafood
89. Evaluation of antiseptic efficacy on skin microbes
90. Isolation of chromium-resistant bacteria
91. Study of antibiotic residues in milk samples
92. Microbial quality of tap water vs filtered water
93. Isolation of endospore-forming bacteria
94. Bacteriological study of soil under different fertilizers
95. Isolation of plant growth-promoting rhizobacteria
96. Study of bacterial contamination in hospital wards
97. Microbial production of bioethanol from waste materials
98. Antibacterial properties of green tea extract
99. Isolation of nitrifying bacteria from aquatic environments
100. Study of yeast isolates from traditional fermented foods
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Microbiology Project Topics List (101-200)
101. Genetic engineering of bacteria for bioplastic production
102. Biotechnological applications of extremophiles
103. Molecular identification of antibiotic-resistant genes
104. Industrial production of enzymes by microbial fermentation
105. Study of quorum sensing in Pseudomonas aeruginosa
106. Bioleaching of metals using bacteria
107. Microbial fuel cell development for clean energy
108. Genomic analysis of probiotic bacteria
109. Microbial biosurfactant production
110. Development of microbial biosensors
111. Bacteriophage therapy against bacterial infections
112. Metagenomic study of soil microbial communities
113. Study of CRISPR-Cas system in bacteria
114. Microbial production of biodegradable plastics
115. Fermentation optimization for citric acid production
116. Microbial hydrogen production
117. Role of microbes in wastewater treatment
118. Cloning and expression of microbial enzymes
119. Microbial corrosion of metals
120. Screening of bacteria for vitamin B12 production
121. Comparative genomics of antibiotic-producing bacteria
122. Role of microorganisms in carbon cycling
123. Metabolic engineering for enhanced ethanol yield
124. Study of secondary metabolite pathways in actinomycetes
125. Microbial production of biofertilizers
126. Detection of genetically modified microorganisms in food
127. Phylogenetic analysis of soil bacteria
128. Enzyme kinetics of microbial amylases
129. Microbial degradation of crude oil
130. Antimicrobial peptides from microorganisms
131. Microbial synthesis of nanoparticles
132. Biotechnological production of amino acids
133. Study of lactic acid fermentation pathways
134. Microbial degradation of pesticides and herbicides
135. Bioinformatics analysis of microbial genomes
136. Use of microbes in sustainable agriculture
137. Microbial desulfurization of fossil fuels
138. Production of single-cell proteins from waste
139. Bacterial quorum quenching mechanisms
140. Development of microbial biofilms for wastewater treatment
141. Study of bacterial conjugation and plasmid transfer
142. Microbial transformation of steroids
143. Biotechnological potential of marine microbes
144. Microbial biosynthesis of silver nanoparticles
145. Study of extremophilic microbial enzymes
146. Microbial degradation of lignin and cellulose
147. Genetic diversity of microbial communities in compost
148. Microbial production of antibiotics under stress conditions
149. Role of endophytes in plant disease resistance
150. Screening of microbes for organic acid production
151. Optimization of microbial fermentation parameters
152. Microbial production of biodegradable detergents
153. Study of halophilic enzyme applications
154. Microbial degradation of microplastics
155. Role of microbes in carbon sequestration
156. Screening of microbes for natural pigment production
157. Microbial synthesis of gold nanoparticles
158. Molecular characterization of thermophilic bacteria
159. Microbial degradation of hydrocarbons
160. Microbial role in biomineralization
161. Biotechnological use of cyanobacteria
162. Study of antibiotic biosynthesis genes
163. Microbial enhancement of soil fertility
164. Role of algae in wastewater remediation
165. Study of microbial metabolism under stress
166. Production of microbial enzymes using agricultural waste
167. Microbial remediation of e-waste
168. Genomic study of antibiotic resistance spread
169. Biopolymer synthesis by bacteria
170. Study of extremophile adaptation mechanisms
171. Bacteriocin production by lactic acid bacteria
172. Microbial degradation of aromatic hydrocarbons
173. Optimization of fermentation for ethanol production
174. Genetic modification of yeast for high ethanol yield
175. Isolation of cyanobacteria for biofuel production
176. Study of biosynthetic pathways in fungi
177. Microbial bioflocculant production
178. Metabolic profiling of industrially important microbes
179. Microbial nitrogen fixation under salinity stress
180. Study of microbial fermentation for food additives
181. Role of microbes in metal recovery
182. Study of antimicrobial peptide synthesis
183. Biotechnological application of fungal enzymes
184. Microbial conversion of waste glycerol to value-added products
185. Role of fungi in carbon sequestration
186. Comparative study of aerobic vs anaerobic digestion
187. Isolation of bacteria for dye degradation
188. Screening of fungi for lignin peroxidase production
189. Biotransformation of toxic compounds by microbes
190. Role of probiotics in poultry feed
191. Microbial biosynthesis of calcium carbonate
192. Detection of multidrug-resistant bacteria in clinical samples
193. Study of microbial diversity in acidic soils
194. Genetic diversity of endophytic fungi
195. Microbial production of carotenoids
196. Microbial degradation of polystyrene
197. Study of bacterial interaction with heavy metals
198. Role of bacteria in nitrogen cycling
199. Study of bacteriophage resistance mechanisms
200. Comparative proteomic analysis of bacterial strains
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Microbiology Project Topics List (201-300)
201. Antibiotic susceptibility patterns of hospital isolates
202. Study of nosocomial infections in ICU
203. Detection of MRSA in clinical samples
204. Bacteriological analysis of diabetic wound infections
205. Prevalence of multidrug-resistant tuberculosis
206. Microbial etiology of urinary tract infections
207. Study of pathogenic fungi in immunocompromised patients
208. Molecular detection of COVID-19 variants
209. Antibiotic resistance in Pseudomonas aeruginosa
210. Study of biofilm-associated infections
211. Serological detection of dengue virus
212. Microbiological quality of surgical instruments
213. Evaluation of hand sanitizers against hospital isolates
214. Bacterial contamination in dental clinics
215. Fungal infections in cancer patients
216. Detection of extended-spectrum beta-lactamase producers
217. Study of bacterial pathogens in blood infections
218. Bacterial contamination in blood transfusion bags
219. Role of probiotics in antibiotic-associated diarrhea
220. Study of antimicrobial resistance in E. coli
221. Identification of pathogens in respiratory infections
222. Study of opportunistic infections in HIV patients
223. Bacteriological analysis of catheterized urine samples
224. Detection of enteric pathogens in food handlers
225. Study of antibiotic usage in hospitals
226. Isolation of carbapenem-resistant Enterobacteriaceae
227. Role of normal flora in health and disease
228. Seroprevalence of hepatitis B and C infections
229. Bacteriological study of neonatal infections
230. Molecular typing of hospital-acquired bacteria
231. Study of antibiotic stewardship programs
232. Microbial profile of pus samples
233. Detection of Clostridium difficile toxin in stool
234. Study of fungal keratitis
235. Microbial contamination of blood transfusion bags
236. Prevalence of Staphylococcus in nasal carriers
237. Detection of Helicobacter pylori in gastric samples
238. Bacteriological quality of drinking water in hospitals
239. Evaluation of natural extracts as antiseptics
240. Study of antimicrobial resistance in Salmonella
241. Detection of pathogens in septicemia patients
242. Study of mycobacterial infections using PCR
243. Identification of dermatophytes from skin scrapings
244. Microbiological analysis of dental plaques
245. Study of microbial load in hospital environments
246. Antibiotic resistance profiling of Klebsiella species
247. Bacterial infections associated with indwelling devices
248. Role of probiotics in urinary infections prevention
249. Detection of bloodstream infections using automated systems
250. Study of pathogenic bacteria from sore throat samples
251. Bacteriological profile of ear infections
252. Detection of fungal infections in immunocompromised hosts
253. Comparative study of antiseptic hand washes
254. Study of biofilm formation in urinary isolates
255. Detection of MRSA using molecular techniques
256. Microbial profile of diabetic foot ulcers
257. Study of nosocomial infections in post-operative wounds
258. Identification of antibiotic-resistant genes
259. Microbial contamination in dialysis water
260. Bacteriological examination of hospital linen
261. Detection of enteric bacteria in fecal samples
262. Study of bacterial pathogens in eye infections
263. Antifungal susceptibility testing of Candida species
264. Evaluation of disinfectants in hospital cleaning
265. Detection of Legionella in hospital water systems
266. Prevalence of Salmonella in eggs and poultry
267. Identification of bacteria in surgical site infections
268. Serological testing for leptospirosis
269. Study of antibiotic resistance patterns in Gram-negative bacteria
270. Detection of zoonotic bacterial infections
271. Bacteriological profile of throat infections
272. Evaluation of probiotic potential of lactobacilli
273. Detection of pathogenic E. coli from fecal samples
274. Study of virulence factors in Staphylococcus aureus
275. Detection of hepatitis viruses using ELISA
276. Microbial flora in chronic respiratory infections
277. Study of fungal infections in hospital environments
278. Antimicrobial potential of plant extracts on wound bacteria
279. Detection of enteric viruses in sewage
280. Study of multidrug resistance in Pseudomonas isolates
281. Serological detection of brucellosis
282. Bacteriological analysis of conjunctivitis samples
283. Detection of Mycoplasma pneumoniae
284. Study of antibiotic cross-resistance mechanisms
285. Molecular detection of antibiotic resistance genes
286. Study of microbial contamination in hospital ICUs
287. Prevalence of fungal infections in diabetic patients
288. Study of nosocomial infections caused by Gram-positive bacteria
289. Study of disinfectant resistance in hospital bacteria
290. Prevalence of methicillin-resistant coagulase-negative staphylococci
291. Study of antifungal resistance in Candida
292. Seroprevalence of toxoplasmosis
293. Detection of rotavirus in children
294. Study of hospital bioaerosols
295. Identification of multidrug-resistant Acinetobacter
296. Role of hospital hygiene in infection control
297. Detection of antimicrobial residues in food
298. Molecular detection of Mycobacterium tuberculosis
299. Study of bacterial endotoxin production
300. Evaluation of UV sterilization efficiency
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Microbiology Project Topics List (301-400)
301. Role of soil microbes in sustainable agriculture
302. Isolation of phosphate-solubilizing microorganisms from rhizosphere soil
303. Nitrogen fixation efficiency of Rhizobium species in legumes
304. Study of microbial inoculants as biofertilizers
305. Isolation of plant growth-promoting bacteria from crop roots
306. Study of microbes involved in organic waste composting
307. Role of mycorrhizal fungi in plant nutrient uptake
308. Isolation of drought-tolerant soil microbes
309. Effect of pesticides on soil microbial biodiversity
310. Microbial degradation of herbicide residues in soil
311. Isolation of cellulolytic microorganisms from agricultural waste
312. Study of microbial diversity in paddy field soil
313. Role of endophytic bacteria in crop improvement
314. Microbial degradation of plastic mulch residues
315. Biofertilizer production using Azotobacter species
316. Impact of heavy metals on soil microflora
317. Comparative analysis of microbial populations in organic vs inorganic farms
318. Isolation of microbes for biocontrol of plant pathogens
319. Study of nitrogen-fixing cyanobacteria in rice paddies
320. Bioremediation of pesticide-contaminated soil
321. Evaluation of compost quality using microbial indicators
322. Isolation of antagonistic bacteria against Fusarium species
323. Role of Bacillus subtilis in disease suppression
324. Screening of fungi for phosphate solubilization
325. Microbial community analysis in forest soils
326. Study of rhizosphere microflora of medicinal plants
327. Role of microbes in nutrient cycling
328. Isolation of arbuscular mycorrhizal fungi from crop fields
329. Microbial conversion of agricultural waste into biofertilizers
330. Study of microbial degradation of lignocellulose
331. Isolation of thermophilic actinomycetes from compost piles
332. Evaluation of microbial bioinoculants on crop yield
333. Role of bacteria in biocontrol of nematodes
334. Study of microbial diversity in saline agricultural soils
335. Isolation of siderophore-producing bacteria
336. Screening of microbes for phytohormone production
337. Impact of fertilizer use on soil microbial balance
338. Isolation of nitrogen-fixing Azospirillum species
339. Study of beneficial fungi in organic farming systems
340. Microbial degradation of pesticides by white rot fungi
341. Role of microbes in nitrogen mineralization
342. Comparative study of rhizobial efficiency in legumes
343. Isolation of cellulolytic bacteria from compost
344. Microbial production of gibberellic acid
345. Impact of GM crops on soil microbial communities
346. Study of microbial succession in decomposing plant material
347. Biocontrol potential of Trichoderma species
348. Study of phosphate-mobilizing fungi
349. Role of microbes in sustainable soil management
350. Effect of temperature on nitrogen fixation
351. Isolation of endophytic bacteria for plant growth promotion
352. Role of microbial inoculants in seed germination
353. Study of microbial carbon sequestration in soil
354. Microbial role in degradation of synthetic fertilizers
355. Isolation of fungi capable of cellulose degradation
356. Bioaugmentation for soil fertility restoration
357. Role of microbes in greenhouse gas mitigation
358. Study of nitrogen-fixing bacteria in non-leguminous plants
359. Microbial activity under drought stress
360. Isolation of sulfur-oxidizing bacteria from soil
361. Role of microorganisms in organic carbon stabilization
362. Biotechnological use of microbes for crop residue management
363. Study of microbial activity in flooded soil
364. Isolation of phosphate-solubilizing actinomycetes
365. Microbial role in detoxification of heavy metals
366. Comparative microbial analysis of contaminated vs non-contaminated soils
367. Isolation of fungi from decaying leaf litter
368. Study of microbial communities in vermicompost
369. Role of nitrogen fixers in sustainable rice cultivation
370. Microbial degradation of organophosphates
371. Evaluation of microbial inoculants in maize cultivation
372. Role of microbes in biological nitrogen fixation
373. Microbial biotransformation of agrochemicals
374. Study of cyanobacterial diversity in agricultural ponds
375. Isolation of beneficial microbes from compost tea
376. Microbial control of root-knot nematodes
377. Role of soil microorganisms in detoxification of pollutants
378. Isolation of beneficial microbes from earthworm castings
379. Study of microbial indicators of soil health
380. Biotechnological improvement of biofertilizers
381. Role of microbes in soil pH regulation
382. Microbial control of phytopathogenic fungi
383. Study of symbiotic nitrogen fixation efficiency
384. Isolation of phosphate-solubilizing yeasts
385. Microbial degradation of crop residues under different moisture levels
386. Role of actinomycetes in plant growth promotion
387. Biodegradation of farm plastic waste using bacteria
388. Study of microbial consortium for organic waste management
389. Isolation of cyanobacteria for biofertilizer production
390. Role of microbes in nitrogen recycling in forest ecosystems
391. Study of endophytic fungi in medicinal plants
392. Microbial degradation of insecticides
393. Isolation of nitrogen-fixing bacteria from legume nodules
394. Role of microbes in biogeochemical cycles
395. Study of microbial response to soil salinity
396. Microbial activity in heavy metal–contaminated soil
397. Role of actinomycetes in soil fertility improvement
398. Isolation of beneficial fungi from rhizosphere soil
399. Role of microbes in soil organic matter decomposition
400. Study of nitrogen-fixing bacteria in paddy soil
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Microbiology Project Topics List (401-500)
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